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SGI 1027, DNA methyltransferase inhibitor, Each

1,766.10

Details

SGI 1027 is a DNA methyltransferase inhibitor. Inhibits the mammalian DNA methyltransferases DNMT3B, DNMT3A and DNMT1 (IC50 values are 7.5, 8 and 12.5 μM with Poly(dl-dC) as the substrate). Reactivates silenced tumor suppressor genes by reducing CpG island hypermethylation.

Additional Information

SKU 10202790
UOM Each
UNSPSC 41116105
Manufacturer Part Number 5155/50