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PMX 53, Potent C5a receptor antagonist, Each

539.40

Details

PMX 53 is a potent C5a receptor antagonist (IC50 = 20 nM). Also MrgX2 agonist. Stimulates MrgX2-mediated mast cell degranulation. Also inhibits C5a-induced hypernociception in rats, inhibits lung metastasis in a mouse breast cancer model and reduces atherosclerotic lesions in a mouse model of atherosclerosis. Negative Control also available.

Additional Information

SKU 10498795
UOM Each
UNSPSC 41116105
Manufacturer Part Number 5473/1