NBQX disodium salt, Potent AMPA antagonist; more water soluble form of NBQX (Cat. No. 0373), Each

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NBQX disodium salt is a selective and competitive AMPA and kainate receptor antagonist (IC50 = 0.15 μM and 4.8 μM, respectively). NBQX blocks the antidepressant effects of 8-Hydroxy-DPAT hydrobromide (Cat. No. 0529), decreases mTOR and BDNF levels. NBQX is neuroprotective, anticonvulsant, antinociceptive and active in vivo. NBQX disodium salt is a more water-soluble form of NBQX (Cat. No. 0373).