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Mps1-IN-1 dihydrochloride, Selective Mps1 kinase inhibitor, Each

675.12

Details

Mps1-IN-1 dihydrochloride is a selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 367 nM); exhibits >1000 fold-selectivity against a panel of 352 kinases with the exceptions of ALK and Ltk. Disrupts the recruitment of Mad2 to kinetochores. Increases frequency of multipolar mitosis in U2OS cells.

Additional Information

SKU 10478002
UOM Each
UNSPSC 41116105
Manufacturer Part Number 5142/10