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LY 2389575 hydrochloride, Selective negative allosteric modulator of mGlu3, Each

411.75

Details:

LY 2389575 hydrochloride is a selective negative allosteric modulator of mGlu3 (IC50 = 190 nM). Exhibits > 65-fold selectivity for mGlu3 over other mGlu receptors. Abolishes the neuroprotective action of LY 379268 against amyloid β toxicity in mixed cortical neuronal and astrocyte cell cultures.

Additional Information

SKU 1641554
UOM Each
UNSPSC 41116105
Manufacturer Part Number 4969/10