$ 892.80
Details
ER gene consists of more than 140kb of genomic DNA divided into 8 exons, being translated into a protein with six functionally discrete domains required for transcription activation function, binding to estrogen response element (ERE) constitutive dimerization, binding to heat shock proteins, and ligand recognition. The ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy. Host Species: RabbitIsotype: IgGSpecies Reactivity: Human, Rat, Mouse, Rabbit, Sheep, Pig and Cow. Others not known.Epitope: N-terminalImmunogen: A synthetic peptide from the N-terminus of human estrogen receptor, α proteinMolecular Weight: 67 kDaPositive Control: MCF-7 cells, Breast CACellular Localization: Nuclear Recommended for:Immunohistochemistry (Formalin/paraffin)Western BlottingImmunoprecipitation (Denatured verified) Note:USA: RUO; Int'l: RUO
