Sox2 Mouse, Alexa Fluor 647, Clone: 245610, BD, Mouse Monoclonal Antibody, Each

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The monoclonal antibody 245610 recognizes the Sox2 transcription factor. Sox2 (SRY (sex determining region Y)-box 2) is a member of the SRY-related HMG-box (SOX) family of transcription factors. Sox2 is required for the maintenance of the undifferentiated state of pluripotent stem cells. Complexes of Sox2 with the homeobox transcription factors Oct3/4 and/or Nanog bind to the promoters of a network of genes that are involved in the maintenance of pluripotency and self renewal in stem cells. The 245610 antibody recognizes both human and mouse proteins. Sox2 is also a marker of neural stem cells during embryonic development and in the adult brain.