Pde4 Inhibitor Used To Treat Psoriasis And Psoriatic Arthritis. It Also Decreases Levels Of Inos, Il-23, And Tnf-A, Each

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Apremilast is an inhibitor of phosphodiesterase 4 (pde4) that is clinically used to treat psoriasis and psoriatic arthritis. Apremilast exhibits anti-inflammatory and immunomodulatory activities, increasing levels of camp and il-10 and decreasing levels of inos, il-23, and tnf-a in vitro and in vivo.