Imiquimod, TLR7 Ligand, Applications: Functional, In vitro assay, Ligand Activation, Each

Details

Imiquimod, TLR7 ligand is an imidazoquinoline amine analog to guanosine. As a synthetic molecule of the Imidazoquinoline family, it has potent immunostimulatory activity. Imiquimod has been shown to activate only TLR7, this activation is MyD88 dependant and leads to the induction of the transcription factor NF-kB.Species: Human, MouseSpecificity: Imiquimod is human/mouse TLR7 agonistStimulation of TLR7 can be achieved with 5-10μg/mLRecommended StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.