Moesin Mouse, Unlabeled, Clone: 38, BD, Mouse Monoclonal Antibody, Each

Details

Moesin belongs to a family of proteins that includes ezrin and radixin. These proteins are co-expressed in a variety of cells. They localize to the cytoskeleton and modify interactions between cytoskeletal and membrane proteins. There is approximately 70% homology between moesin and ezrin and 80% homology between moesin and radixin. Moesin is intracellular and contains multiple conserved domains that are putative phosphorylation sites. It has a calculated molecular weight of 67.8 kDa, but migrates in SDS-PAGE at approximately 78 kDa. This discrepancy is likely due to a charged alpha-helical region within the protein.