Calbiochem N-Methyl-D-aspartic Acid, Hydrate, Excitatory amino acid neurotransmitter, Each

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Excitatory amino acid neurotransmitter. Selective agonist of the glutamate receptor that regulates Ca2 channels. Important in long-term potentiation, ischemia, and epilepsy. NMDA receptors are involved in the fine tuning of synaptic connections in the developing brain. Chronic treatment with NMDA produces structural changes in synaptic morphology. Over-excitation of NMDA receptors causes neuronal degeneration and cell death.