anti-MafK/Nfe2u, Polyclonal, Rabbit Polyclonal Antibody, Each

Details

Specifically detects MafK/Nfe2u Clone: in Human, Mouse, Rat samples, and it is validated for ChIP, Chromatin Immunoprecipitation, Western BlottingTranscription factor MafK (UniProt Q61827; also known as Erythroid transcription factor NF-E2 p18 subunit, Nuclear factor erythroid derived 2 ubiquitous, p18 NF-E2) is encoded by the Mafk (also known as Nfe2u, AW061068) gene (Gene ID 17135) in murine species. MafK, MafG and MafF consistute a family of transcription factors that dimerize with the CNC (cap' n' collar) family regulatory protein Nrf2 (NF-E2 p45-related factor 2) via their bZip domain. The Nrf2/small Maf heterodimer regulates downstream genes, including those of phase II detoxifying enzymes, by targeting antioxidant responsive element (ARE) and Maf recognition element (MARE).