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Specifications Synonym(s): 4,4,5,5-Tetramethyl-2-(1H-pyrazol-2-yl)-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(1H-pyrazol-4-yl)-1,3,2-dioxaborolane; 4,4,5,5-Tetramethyl-2-(pyrazol-4-yl)-1,3,2-dioxaborolane; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyrazole; Pyrazol-4-ylboronic acid pinacol esterFormula: (CH3)4C2O2BC3N2H3Formula Weight: 194.04CAS No.: 269410-08-4Purity: 97%Application: Reagent used for• Suzuki-Miyaura cross-couplings • Ruthenium-catalyzed asymmetric hydrogenation Reagent used in preparation of inhibitors of many highly significant therapeutic enzymes and kinases containing the privileged scaffold pyrazole, including• VEGF • Aurora3,• Rho (ROCK)• Janus Kinase 2 (JAK) • c-MET • ALK • S-nitrosoglutathione reductase • CDC7 • Acetyl-CoA carboxylase • Prosurvival Bcl-2 protein • Viral RNA-Dependent RNA polymerase • Long Chain Fatty Acid Elongase 6• PI3 • AKT • Chk1 • Protein Kinase BLegal Information: Product of Boron MolecularPackaging: 1, 5, 25 g in glass bottleMelting Point: 142-146°C(lit.)Empirical Formula (Hill Notation): C6H7FN2
