1,8-Diazabicyclo[5.4.0]undec-7-ene 100G UN 3267 8/PG 2, Each

Details

Specifications Synonyms: 2,3,4,6,7,8,9,10-Octahydropyrimidol[1,2-a]azepine; DBUCAS Number: 6674-22-2Formula: C9H16N2Formula Weight: 152.24Linear Formula: C9H16N2MDL No.: MFCD00006930Purity: 0.98Boiling Point: 80-83 C/0.6 mmHg(lit.)Density: 1.018 g/mL at 25 C(lit.)Refractive Index: n20/D 1.522-1.524(lit.)Beilstein Registry Number: 508906EC Number: 229-713-7UNSPSC Code: 12352302Features and Benefits: Strong hindered amine base.General description: 1,8-Diazabicyclo[5.4.0]undec-7-ene is a bicyclic amidine base. It is non-nucleophilic, sterically hindered, tertiary amine base in organic chemistry. It is reported to be superior to amine catalyst in Baylis-Hillman reaction. It promotes the methylation reaction of phenols, indoles and benzimidazoles with dimethyl carbonate under mild conditions.Application: Used in a new synthesis of the ABCD ring system of Camptothecin.Application: 1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) may be used:. as catalyst for carboxylic acid esterification with dimethyl carbonate . in the synthesis of duocarmycin and CC-1065 analogs . as catalyst in aza-Michael addition and Knovenegal condensation reaction. as base for dehalogenation of halogenated Diels-Alder adducts and the resulting activated 2,4-dienones were subjected to regio- and stereo-directed Michael additions, using Yamamoto′s reagent (CH3Cu · BF3). in a new synthesis of the ABCD ring system of CamptothecinApplication: 1,8-Diazabicyclo[5.4.0]undec-7-ene may be used as an catalyst for the dissolution and activation of cellulose by a reversible reaction of its hydroxyl groups with carbon dioxide. This dissolved cellulose system can be derivatized to form cellulose mixed esters.RIDADR: UN 3267 8 / PGIIWGK Germany: 2Flash Point(F): 240.8 FFlash Point(C): 116 CR Codes: 22-34-52/53S Codes: 26-36/37/39-45-61IOD Codes: CSymbol: GHS05, GHS06Signal Word: DangerHazard Statements: H290-H301-H314-H412Precautionary statements: P273-P280-P301 P310-P305 P351 P338-P310